PRiSM Study

Patient Response to Spinal Manipulation (PRiSM) will measure and compare the movement and muscle activity of the lower back before and after a chiropractic treatment. This will lead to a better understanding of the therapeutic mechanism of a chiropractic adjustment.

We are currently screening participants with low back pain and between the ages of 21 and 64 for this study. If you are interested, please contact us

ACT1, ACT2 and ACT3 Studies

The Palmer Center for Chiropractic Research, RAND Corporation and Samueli Institute received a $7.4 million grant in February of 2011 from the Congressionally Directed Medical Research Program within the Department of Defense. This award is the largest in the history of the chiropractic profession. Through three clinical trials, the ACT studies will assess the effectiveness of chiropractic in military personnel.

This study is not screening participants at the Palmer Research Clinic as it is taking place on U.S. military bases.

CHiP Study

The Chiropractic for Hypertension in Patients (CHiP) study was designed to look at blood pressure changes in participants who received a specific chiropractic treatment. It has completed recruitment.


The Collaborative Care for Older Adults (COCOA) study will evaluate co-management practice models between medical doctors and doctors of chiropractic. Recruitment concluded in July 2012.

MCD Study

The MCD Study will assess three gentle types of chiropractic treatment for people between the ages of 18 and 70 with neck pain or pain in their shoulders, arms or hands that may come from the neck. Recruitment concluded in September 2013.