Funding Source: NIH/NCCAM
Award Amount: 3,537,049
Funding Period: 6/2008 – 5/2015
Principal Investigator: Goertz, Christine Ph.D.
Clinic and Data Core Leaders: Cynthia Long, PhD, Robert Vining, DC, DHSc
Palmer Center for Chiropractic Research (PCCR) established a 4-year multidisciplinary Developmental Center to increase the level and quality of our ongoing research program by enhancing our ability to conduct clinical research, to advance scientific expertise and research infrastructure, and to support enhanced communication and partnering among 10 investigators at Palmer College of Chiropractic, the University of Iowa, Mt Sinai Medical Center, Mines VA Hospital (VA), and Loyola University Stritch School of Medicine. The long-range importance of this approach is that it provides valuable information for understanding the appropriate clinical role of spinal manipulation in our evolving healthcare system. Four clinical trials were conducted.
Project 1: Patient Response to Spinal Manipulation (PRiSM)
Co-Leaders: Ting Xia, PhD, David Wilder, PhD.
Co-Investigators: Cynthia Long, PhD, James DeVocht, DC, PhD, M. Ram Gudavalli, PhD, Robert Vining, DC, DHsc
Project 2: Conservative Treatment of Patiesn with Temporamandibular Disorders
Co-Leaders: James DeVocht, DC, PhD, Clark Stanford, DDS, PhD
Co-Investigators: Cynthia Long, PhD, Maria Hondras, DC, MPH, PhD, Walter Schaeffer, DC Project 3: Cervical Distraction Sham Development: Translating from Basic to Clinical Studies
Co-Leaders: M. Ram Gudavalli, PhD, Avinash Patwardhan, PhD
Co-Investigators: Cynthia Long, PhD, Charles Henderson, DC, PhD, Robert Havey, BS, Leonard Voronov, MD, PhD, Alexander Ghanayem, MD, Robert Vining, DC, DHsc
Xia T, Long CR, Vining RD, Gudavalli MR, DeVocht JW, Kawchuk GN, Wilder DG, Goertz CM. Association of lumbar spine stiffness and flexion-relaxation phenomenon with patient-reported outcomes in adults with chronic low back pain – a single-arm clinical trial investigating the effects of thrust spinal manipulation. BMC Complement Altern Med 2017;17(303).
Goertz CM, Xia T, Long CR, Vining RD, Pohlman KA, DeVocht JW, Gudavalli MR, Owens EF, Meeker WC, Wilder DG. Effects of spinal manipulation on sensorimotor function in low back pain patients – a randomized controlled trial. Man Ther 2016;21:183-190.
Goertz CM, Salsbury SA, Vining RD, Long CR, Pohlman KA, Weeks WB, Lamas GA. Effect of spinal manipulation of upper cervical vertebrae on blood pressure: results of a pilot sham-controlled trial. J Manipulative Physiol Ther 2016;39(5):369-380.
Gudavalli MR, Salsbury SA, Vining RD, Long CR, Corber L, Patwardan AG, Goertz CM (2015). Development of an attention-touch control for manual cervical distraction: a pilot randomized clinical trial for patients with neck pain. Trials 16:259.
Gudavalli MR, Salsbury SA, Vining RD, Long CR, Corber L, Patwardhan, AG, Goertz CM. Development of an attention-touch control for manual cervical distraction: a pilot randomized clinical trial for patients with neck pain. Trials. 2015; 16:259. Published 2015 Jun 5. doi:10.1186/s13063-015-0770-6
Xia T, Wilder DG, Gudavalli MR, DeVocht, Vining RD, Pohlman, Kawchuk GN, Long CR, Goertz CM. Study protocol for patient response to spinal manipulation – a prospective observational clinical trial on physiological and patient-centered outcomes in patients with chronic low back pain. BMC Complement Altern Med. 2014; 14:292. Published 2014 Aug 8. doi:10.1186/1472-6882-14-292
DeVocht JW, Goertz CM, Hondras MA, Long CR, Schaeffer W, Thomann L, Spector M, Stanford CM (2013). A pilot study for a chiropractic intervention for management of TMD orafacial pain. The Journal of the American Dental Association 144(10):1154-1163.
Wilder DG, Vining RD, Pohlman KA, Meeker WC, Xia T, DeVocht JW, Gudavalli RM, Long CR, Owens EF, Goertz CM (2011). Effect of spinal manipulation on sensorimotor functions in back pain patients: study protocol for a randomised controlled trial. Trials 12:161.