Funding Source: NIH/NCCIH UG3/UH3AT009761
Award Amount: $7,087,730
Performance Period: 09/20/2017 – 08/31/2023
Principal Investigators: Cynthia Long, Ph.D; Christine Goertz, D.C., Ph.D
Co-Investigators: Thad Abrams, M.D., M.S., Richard Branson, D.C., Kei-Hoi Cheung, Ph.D., Sally Haskell, M.D., Erin Krebs, M.D., M.P.H., Anthony Lisi, D.C., Jon Lurie, M.D., M.S., Stacie Salsbury, Ph.D, Paul Shekelle, M.D., Ph.D, Robert Vining, D.C., D.H.Sc., Robert Wallace, M.D., M.Sc.
Clinical Research Specialist: Elissa Twist, D.C., M.S., CCRP
Study Coordinators: Anna Walden-Cobb, D.C., M.S., CCRC at Iowa City VA, Courtney Karnopp, BS at Minneapolis VA, Rebecca Rudquist at Minneapolis VA, Kena McDermott, D.C., M.S. at VA Connecticut and Melvin Valle, B.S. at VA Greater LA Healthcare System
Collaborating Institutions: VA Connecticut Healthcare System, Minneapolis VA Health Care System, Iowa City VA Health Care System, VA Greater LA Healthcare System, University of Iowa College of Public Health, Yale University Center for Medical Informatics, The Dartmouth Institute for Health Policy & Clinical Practice, Duke Clinical Research Institute
Description: Two linked RCTs in four VA sites in veterans with chronic LBP; Phase 1: low dose (1-5 visits) vs. high dose (8-12 visits) over 10 weeks; Phase 2: scheduled monthly chiropractic visits vs. no chiropractic visits over 42 weeks.
Long CR, Lisi AJ, Vining RD, Wallace RB, Salsbury SA, Shannon ZK, Halloran S, Minkalis AL, Corber L, Shekelle PG, Krebs EE, Abrams TE, Lurie JD, Goertz CM. Veteran Response to Dosage in Chiropractic Therapy (VERDICT): Study Protocol of a Pragmatic Randomized Trial for Chronic Low Back Pain. Pain Med. 2020 Dec 12;21(Suppl 2):S37-S44. doi: 10.1093/pm/pnaa289. PMID: 33313732; PMCID: PMC7734654.
Bastian LA, Cohen SP, Katsovich L, Becker WC, Brummett BR, Burgess DJ, Crunkhorn AE, Denneson LM, Frank JW, Goertz C, Ilfeld B, Kanzler KE, Krishnaswamy A, LaChappelle K, Martino S, Mattocks K, McGeary CA, Reznik TE, Rhon DI, Salsbury SA, Seal KH, Semiatin AM, Shin MH, Simon CB, Teyhen DS, Zamora K, Kerns RD; NIH-DOD-VA Pain Management Collaboratory. Stakeholder Engagement in Pragmatic Clinical Trials: Emphasizing Relationships to Improve Pain Management Delivery and Outcomes. Pain Med. 2020 Dec 12;21(Suppl 2):S13-S20. doi: 10.1093/pm/pnaa333. PMID: 33313726; PMCID: PMC7824996.
Vining RD, Shannon ZK, Salsbury SA, Corber L, Minkalis AL, Goertz CM. Development of a Clinical Decision Aid for Chiropractic Management of Common Conditions Causing Low Back Pain in Veterans: Results of a Consensus Process. J Manipulative Physiol Ther. 2019 Nov;42(9):677-693. doi: 10.1016/j.jmpt.2019.03.009. Epub 2019 Dec 19. PMID: 31864769; PMCID: PMC7183425.
Administrative supplement funding provides one to two years of in-depth research experiences for doctors of chiropractic: Stephanie Halloran, D.C., M.S.; Zacariah Shannon, D.C., M.S.; Gregory Roytman, D.C.; and Anna-Marie Ziegler, M.M., D.C. They are being mentored by investigators at the Palmer Center for Chiropractic Research and the Yale Center for Medical Informatics. In these roles, they actively participated in the planning phase and now implementation of VERDICT, the large, pragmatic clinical trial studying optimal dose of chiropractic care.