Funding Source: NIH/NCCIH
Grant Number: R15-AT009612
Award Amount: $451,522
Funding Period: 07/05/2017 – 06/30/2020
Principal Investigators: Stephen Onifer, Ph.D. and Bradley K. Taylor, Ph.D. (University of Pittsburgh)
Co-Investigators: Cynthia Long, Ph.D.
Laboratory Support: Randall Sozio, B.S., LATG, Charlie Arends, B.S.
Collaborative Institution: University of Pittsburgh
This project was a collaboration between the Palmer Center for Chiropractic Research (PCCR) and the University of Pittsburgh. The grant funded a three-year research project to learn more about the underlying factors of pain relief following spinal manipulative therapy. The project also included a student research training component, the first of its kind at a chiropractic college.
(Research Honors) Salata V, Sheridan C, Arends C, Vande Hei A, Sozio R, Long C, Shannon Z, Taylor B, Onifer S. Establishing Laboratory Methods for Determining the Contribution of Neuropeptide Y to the Pain Relief of Spinal Manipulative Therapy. ACC-RAC Conference, March 19-21, 2020, San Diego, CA. (Poster)
(Research Honors) Jones W, Bishop A, Arko C, Arends C, Sozio R, Onifer S. Engaging Chiropractic Students in Basic Research Measuring Serum IL-1a Levels in a Spared Nerve Injury (SNI) Rat Peripheral Neuropathic Pain Model. ACC-RAC Conference, March 19-21, 2020, San Diego, CA. (Poster)
Onifer SM, Sozio RS, Long CR. Role of Endocannabinoids in Manipulative Therapy Analgesia? Society for Neuroscience Conference, October 19-23, 2019, Chicago, IL. (Poster)
(Research Honors) Jordan MC, Vande Hei AG, Arends CJ, Sozio RS, Vining RD, Hoyt K, Long CR, Jones W, Taylor BK, Onifer SM. Providing Chiropractic College Students with National Institutes of Health-funded Basic Neuroscience Research Opportunities. Society for Neuroscience Conference, October 19-23, 2019, Chicago, IL. (Poster)
Onifer SM. Experimental Spinal Manipulative Therapy Analgesia. Osher Center for Integrative Medicine, Harvard Medical School & Brigham and Women’s Hospital, June 13, 2018, Boston, MA. (Invited Presentation)
Onifer SM, Sozio RS, DiCarlo DM, Li Q, Donahue RR, Taylor BK, Long CR. Modeling Spinal Manipulative Therapy for Studies of Analgesia in Chronic Experimental Pain. International Congress on Integrative Medicine and Health, May 8-11, 2018, Baltimore, MD. (Poster)
Onifer S, Sozio R, DiCarlo D, Li Q, Donahue R, Taylor B, Long C. Rate-Dependent Anti-Nociceptive Effect of a Spinal Manipulative Therapy on Adult Rat Chronic Peripheral Neuropathic Pain Behavior. DC 2017, March 16-18, 2017, Washington, DC. (Poster)
Onifer SM, Sozio RS, Long CR. Role for endocannabinoids in spinal manipulative therapy analgesia?. Evid Based Complement Alternat Med 2019; Article ID: 2878352
Onifer SM, Sozio RS, DiCarlo DM, Li Q, Donahue RR, Taylor BK, Long CR. Spinal manipulative therapy reduces peripheral neuropathic pain in the rat. NeuroReport 2018;29(3):191-196.